CYTOKINE RELEASE SYNDROME (CRS)

 

CRS is simply due to massive T-cell stimulation and cytokine storm, most often seen in CAR-T therapy and hematopoeitic stem cell transplants (HSCT)/BiTE therapy in cancer patients, but also in severe viral infections (commonly respiratory, like influenza), severe bacterial/fungal infections, HLH and MAS...

 NATURE IMMUNE RESPONSE (CHINA)

 

More than 100 years since the outbreak of the 1918 influ- enza pandemic, we now seem to face another pandemic. The outbreak of the new coronavirus (SARS-CoV-2) infection is spreading to every continent, forcing us to live with  this  virus  for  perhaps  a  long  time...

 JHLT COVID-19 NATIVE STAGING PROPOSAL (USA)

 

COVID-19 Illness in Native and Immunosuppressed States: A Clinical-Therapeutic Staging Proposal...

LANCET ID SARS-COV2 HOST RESPONSE (CHINA)

 

Since December, 2019, coronavirus disease 2019 (COVID-19)  has affected more than 100 000 patients globally.1 COVID-19   is  caused by  the  severe acute respiratory syndrome...